Endometrial Cancer Jemperli Print Save Jemperli Generic name: dostarlimab-gxly Dosage form: injection Drug class: Anti-PD-1 monoclonal antibodies Medically reviewed by Judith Stewart, BPharm. Last updated on Jun 28, 2022. Uses Warnings Before taking Side effects Interactions Dosage What is Jemperli? signs of a hormonal disorder --frequent or unusual headaches, dizziness, feeling very weak, mood or behavior changes, hoarse or deepened voice, increased hunger or thirst, increased urination,.
seizure, confusion, hallucinations, eye pain or redness, vision problems, severe stomach pain, nausea, vomiting, diarrhea, bloody or tarry stools, pale skin, tiredness, severe stomach pain, nausea, vomiting, diarrhea, bloody or tarry stools; low red blood cells (anemia) --pale skin, tiredness, cold hands and feet; low white blood cell counts --fever, mouth sores,.
4.5 Rating View Profile Your doctor may stop your treatment for some time if you get serious side effects. Your doctor may also prescribe another medication (a corticosteroid such as.
swelling of your face, lips, tongue, or throat, fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling, lightheadedness , chills, itching, shortness of breath, new or worsening cough, chest pain, irregular heartbeats, seizure , confusion, hallucinations, eye pain or redness, vision problems,
severe stomach-area (abdomen) pain or tenderness Liver problems. yellowing of your skin or the whites of your eyes severe nausea or vomiting pain on the right side of your stomach area (abdomen) dark urine (tea colored) bleeding or bruising more easily than usual Hormone gland problems. headaches that will not go away or unusual headaches
• Do not shake. • For the 500-mg dose, withdraw 10 mL of JEMPERLI from a vial using a disposable sterile syringe made of polypropylene and dilute into an intravenous infusion bag containing 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP to a final concentration between 2 to 10 mg/mL (maximum 250 mL).
Fatigue/asthenia, nausea, diarrhea, anemia, constipation; sepsis, acute kidney injury, UTI, abdominal pain, pyrexia; other immune-mediated adverse reactions (eg, ocular, gastrointestinal,.
The most common side effects of JEMPERLI include tiredness and weakness, low red blood cell count (anemia), diarrhea, nausea, decreased number of certain white blood cells, decreased albumin in the blood, increase in certain liver blood tests, decreased salt (sodium) in the blood. These are not all of the possible side effects of JEMPERLI.
Most common adverse reactions (≥20%) are fatigue/asthenia, nausea, diarrhea, anemia, and constipation. (6.1) To report SUSPECTED ADVERSE REACTIONS, contact GlaxoSmithKline at 1-888-825-5249 or FDA.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the.
Most common adverse reactions (≥20%) in patients with dMMR solid tumors are fatigue/asthenia, anemia, diarrhea, and nausea. Most common Grade 3 or 4 laboratory abnormalities (≥2%) are decreased lymphocytes, decreased sodium, increased alkaline phosphatase, and decreased albumin. (6.1)
[formulation clarification] Info: nonproprietary name = dostarlimab-gxly [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments mismatch repair deficient endometrial CA, recurrent or advanced [1000 mg IV q6wk, starting wk 13]
Jemperli is given by infusion (drip) into a vein over 30 minutes. The dose is 500 mg once every 3 weeks for the first 4 doses and then 1,000 mg every 6 weeks. Treatment can be continued as long as Jemperli continues to work. The doctor may interrupt Jemperli treatment or stop it altogether if certain side effects occur.
What are the possible side effects? JEMPERLI can cause serious and potentially deadly immune reactions including inflammation of the lungs, gut, liver, kidneys, hormonal glands and skin as well as.
These are not all of the possible side effects of JEMPERLI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. General information about the safe and effective use of JEMPERLI. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.
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